Implantation of XEN‑45 for Treatment of Refractory Secondary Glaucoma - Summary - MDSpire

Implantation of XEN‑45 for Treatment of Refractory Secondary Glaucoma

  • By

  • Kun Lv

  • Zhiqiao Liang

  • Kuankuan Wu

  • Yao Ma

  • Kangyi Yang

  • Wenbo Liu

  • Huijuan Wu

  • November 14, 2025

  • 0 min

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Objective:

To present data on XEN-45 gel stent implantation for the treatment of refractory secondary glaucoma (SG) in a Chinese patient population, highlighting its significance in improving patient outcomes.

Key Findings:
  • XEN-45 gel stents effectively manage various forms of refractory secondary glaucoma, with a reported success rate of X%.
  • The ab externo implantation techniques resulted in minimal intraocular manipulation and rapid recovery, with a complication rate of Y%.
  • The study included diverse SG cases, enhancing the understanding of XEN-45's applicability across different patient demographics.
Interpretation:

The XEN-45 gel stent is a promising minimally invasive option for patients with refractory secondary glaucoma, potentially reducing complications associated with traditional surgeries, such as hypotony and bleb leaks.

Limitations:
  • The study's sample size and follow-up duration may limit the generalizability of the findings, particularly in diverse populations.
  • Comparative analyses with other surgical techniques were not included, which may affect the robustness of the conclusions drawn.
Conclusion:

XEN-45 gel stent implantation is a viable treatment for refractory secondary glaucoma, offering a safer alternative to traditional surgical methods, with implications for improving patient management strategies.

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