Prevalence and Management of Complications of Laser Ablation for Benign Thyroid Nodules - Summary - MDSpire

Prevalence and Management of Complications of Laser Ablation for Benign Thyroid Nodules

  • By

  • Lorenzo Scappaticcio

  • Nicole Di Martino

  • Pamela Ferrazzano

  • Maria Ida Maiorino

  • Paola Caruso

  • Alessandra Volatile

  • Miriam Longo

  • Giovanni Docimo

  • Eduardo Iervolino

  • Pierpaolo Trimboli

  • Katherine Esposito

  • Giuseppe Bellastella

  • February 20, 2025

  • 0 min

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Objective:

To assess the prevalence of complications specifically from laser ablation (LA) for benign solid thyroid nodules and their management.

Key Findings:
  • Overall complications prevalence was 23% (CI, 17%-30%, I2 93.7%).
  • Minor complications prevalence was 21% (CI, 15%-27%, I2 93.7%).
  • Major complications prevalence was 2% (CI, 1%-3%, I2 54.0%).
  • Pooled prevalence of local pain was 15% (CI, 12%-20%, I2 89.3%), typically mild to moderate.
  • Dysphonia prevalence was 2% (CI, 1%-2%, I2 30.3%), mostly transient.
Interpretation:

LA for benign noncystic thyroid nodules is generally safe, with major complications being rare.

Limitations:
  • Quality of included studies was judged as fair, which may affect the reliability of the findings.
  • High heterogeneity in complication rates (I2 values) suggests variability in study results.
  • Lack of registration for the systematic review and meta-analysis may limit transparency.
Conclusion:

LA is a valuable and generally safe treatment option for symptomatic benign thyroid nodules, with manageable complications and major complications being rare.

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