A Case Report of Cronkhite-Canada Syndrome in Conjunction with Sigmoid Colon and Early Esophageal Cancers - Summary - MDSpire

A Case Report of Cronkhite-Canada Syndrome in Conjunction with Sigmoid Colon and Early Esophageal Cancers

  • By

  • Wang, Yumeng

  • 孙, 文妍

  • 王, 鼎鑫

  • Fan, QIcheng

  • Huang, Zhihang

  • Bai, Yun

  • April 6, 2026

  • 0 min

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Objective:

To report a rare case of Cronkhite-Canada syndrome (CCS) associated with sigmoid colon cancer and early esophageal cancer.

Key Findings:
  • CCS was diagnosed simultaneously with sigmoid colon cancer and early esophageal cancer.
  • Postoperative symptoms such as diarrhea, hair loss, and malnutrition improved.
  • Gastric-duodenal and colonic polyp-like lesions were reduced after treatment.
Interpretation:

This case highlights the rarity of simultaneous occurrence of colon and early esophageal cancers in patients with CCS and emphasizes the importance of understanding the disease for better management.

Limitations:
  • The case is based on a single patient, limiting generalizability.
  • Long-term outcomes of untreated early esophageal cancer are not well-documented.
Conclusion:

The report aims to enhance understanding of CCS and its associated cancers, advocating for improved diagnosis and treatment strategies.

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