Conceptualizing and treating the polytrauma clinical triad as a complex chronic pain syndrome - Summary - MDSpire

Reframing the Polytrauma Clinical Triad as a Multifaceted Chronic Pain Disorder: Approaches to Treatment

  • By

  • Ajay Manhapra

  • Eamonn Kennedy

  • David Cifu

  • Shannon R. Miles

  • Mary Jo Pugh

  • July 17, 2026

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Objective:

To propose a new interdisciplinary model for managing the polytrauma clinical triad (PCT) as a complex chronic pain syndrome, addressing the significant challenges faced by US Service Members and Veterans.

Approach:
  • FREIDEM Model: The Functional Recovery Enabling Inter-Disciplinary Evaluation and Management (FREIDEM) model conceptualizes PCT as a complex chronic pain syndrome influenced by PTSD, TBI, and other comorbidities, integrating recent clinical advances in treatment.
Key Findings:
  • PCT is prevalent among US Service Members and Veterans, with about 13% meeting diagnostic criteria.
  • Current management strategies are fragmented and often fail to address the complex needs of PCT patients.
  • Many patients show improvement within 5 years, but a significant number experience worsening symptoms despite care.
Interpretation:

The FREIDEM model aims to integrate clinical advances in treating complex chronic pain syndromes and emphasizes the need for a comprehensive treatment plan addressing biopsychosocial impediments.

Limitations:
  • Further research is needed to validate the effectiveness of the FREIDEM model in improving outcomes for patients with PCT.
  • Existing care models are often fragmented and lack a unified approach for managing the complexities of PCT.
Conclusion:

The FREIDEM model provides a framework for treating PCT as a complex chronic pain syndrome.

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