Evaluation of Anterior Segment Measurement Discrepancies Between Sirius Plus and Pentacam AXL - Summary - MDSpire

Evaluation of Anterior Segment Measurement Discrepancies Between Sirius Plus and Pentacam AXL

  • By

  • Jiliang Ning

  • Lijun Zhang

  • April 21, 2026

  • 0 min

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Objective:

To compare the differences, consistencies, and correlations of anterior segment biological parameters measured by Sirius Plus and Pentacam AXL in a healthy myopic population.

Key Findings:
  • No significant differences in anterior flat keratometry, anterior vertical/horizontal astigmatism, and anterior oblique astigmatism at 45° between the two devices.
  • Significant differences were observed in other parameters, including central corneal thickness and anterior chamber depth.
  • Intraclass correlation coefficients for anterior flat keratometry, anterior steep keratometry, and white-to-white were 0.965, 0.963, and 0.932, respectively.
  • Goodness-of-fit analysis showed R2 values >0.85 for several key parameters, indicating strong correlation.
Interpretation:

The study indicates that anterior corneal keratometry and white-to-white measurements are consistent and reliable between the two devices, suggesting their effective use in clinical practice for refractive surgery.

Limitations:
  • The study was limited to a specific population (myopic patients) and may not generalize to other populations, potentially affecting the applicability of the results.
  • Only one eye per participant was measured, which may affect the overall data representation and limit the robustness of the findings.
Conclusion:

Sirius Plus and Pentacam AXL provide comparable measurements for certain anterior segment parameters, suggesting their suitability for clinical applications in refractive surgery.

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