Case Report: Clinicopathological features and outcomes of superficial cervicovaginal myofibroblastoma: analysis of two cases and a review of the literature - Summary - MDSpire

Case Report: Clinicopathological features and outcomes of superficial cervicovaginal myofibroblastoma: analysis of two cases and a review of the literature

  • By

  • Xiaoli Cai

  • Yanli Liu

  • Yunfeng Niu

  • Xiaodan Shen

  • Qian Zhang

  • Lei Liang

  • Shuang Liu

  • May 13, 2026

  • 0 min

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Objective:

To report two cases of superficial cervicovaginal myofibroblastoma (SCVM) and review the existing literature on its clinical manifestations, pathological features, and treatment outcomes, highlighting the significance of these findings for clinical practice.

Key Findings:
  • SCVM is a rare benign tumor, representing less than 0.1% of benign tumors, predominantly affecting women aged 20–60 years.
  • Clinical manifestations include irregular vaginal bleeding and incidental findings.
  • Histopathological diagnosis relies on morphology and immunohistochemical profiles.
  • Surgical excision is the primary treatment, with a favorable prognosis and low recurrence rate.
Interpretation:

SCVM exhibits benign biological behavior and is often misdiagnosed due to overlapping features with other tumors, which can lead to inappropriate management. Accurate diagnosis is crucial for effective treatment.

Limitations:
  • Limited number of reported cases restricts comprehensive understanding of SCVM and its clinical implications.
  • Potential for misdiagnosis or overtreatment due to low clinical awareness, which may adversely affect patient outcomes.
Conclusion:

SCVM is a benign tumor with a favorable prognosis post-surgery. Increased awareness and accurate diagnostic methods are essential for effective management, particularly to avoid misdiagnosis.

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