Objective:

To explore clinical, pathologic, and EEG features that may impact seizure outcomes in patients with PXAs and tumor-related epilepsy.

Approach:

Key Findings:

• 76% of patients with PXA had tumor-related epilepsy.
• The mean age at diagnosis was 32 years, with a range of 10 to 71 years.
• The most frequent tumor location was the temporal lobe (47.4%).
• Higher initial tumor volume trended towards worse seizure outcomes, but this was not statistically significant.
• Gross total resection was performed in 57.8% of patients.

Interpretation:

Limitations:

• Small sample size of 25 patients.
• Limited statistical significance for some findings.
• Potential biases in retrospective data collection.

Conclusion:

Source

Based on findings from:

Epilepsy characteristics and outcomes in patients with pleomorphic xanthoastrocytomas

Cody L. Nathan, Dina Ghandour, Elizabeth M. Cunningham, Rimas V. Lukas, Jared Sullivan, Sean Sachdev, Jessica W. Templer. Journal Of Neuro-Oncology, 2026.

https://link.springer.com/article/10.1007/s11060-026-05607-2

Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.