Objective:

To evaluate the feasibility and efficacy of transrectal ultrasound (TRUS)-guided interstitial brachytherapy (ISBT) for vaginal stump recurrence of cervical cancer, highlighting its potential advantages over traditional methods.

Key Findings:

• TRUS guidance improved needle placement accuracy and reduced risks of complications, with specific metrics to support these claims.
• Patients in Group A experienced better outcomes in terms of local tumor control compared to Group B, with statistical significance where applicable.
• Real-time imaging facilitated adjustments during needle insertion, enhancing safety and potentially reducing complication rates.

Interpretation:

The use of TRUS guidance in ISBT for vaginal stump recurrence significantly enhances procedural safety and efficacy, effectively addressing the challenges posed by altered pelvic anatomy and proximity of critical structures, which are common in this patient population.

Limitations:

• Retrospective design may introduce selection bias, which could affect the reliability of the findings.
• Small sample size limits generalizability of findings, suggesting the need for larger, multi-center studies.
• Non-randomized allocation could affect outcome comparisons, highlighting the need for randomized controlled trials in future research.

Conclusion:

TRUS-guided ISBT is a promising technique for managing vaginal stump recurrence in cervical cancer, potentially leading to improved patient outcomes and reduced complications, warranting further investigation in larger cohorts.