Objective:

To evaluate plasma activity of selected matrix metalloproteinases (MMPs) in individuals with morbid obesity and the impact of laparoscopic sleeve gastrectomy on MMPs’ activity.

Approach:

Key Findings:

• Increased activities of MMPs were observed in morbidly obese women without metabolic syndrome before surgery.
• Higher activities of MMP-1, MMP-3, MMP-10, and MMP-12 were found in morbidly obese women with metabolic syndrome compared to lean controls.
• Post-surgery, only some plasma MMP activities partially normalized in both obese groups.
• MMPs activity did not differ significantly between obese individuals with and without metabolic syndrome.

Interpretation:

Remove unsupported conclusions and focus on the findings as presented in the source.

Limitations:

• The study was limited to a small sample size of 63 women.
• Long-term effects beyond 12 months were not assessed.

Conclusion:

Revise to state only that further long-term studies are needed without additional implications.

Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.