Development and Preliminary Validation of ORCA-PD, an Online Rapid Cognitive Assessment for Parkinson Disease: Mixed Methods Study - Summary - MDSpire

Development and Preliminary Validation of ORCA-PD, an Online Rapid Cognitive Assessment for Parkinson Disease: Mixed Methods Study

  • By

  • Avigail Lithwick Algon

  • Sarah Brisman

  • Chi-Ying R Lin

  • William Saban

  • June 8, 2026

  • 0 min

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Objective:

To evaluate the feasibility and preliminary validity of ORCA-PD as a remote, self-administered cognitive screening tool tailored for Parkinson's Disease (PD), addressing the critical need for accessible cognitive evaluations.

Key Findings:
  • The ORCA-PD was feasible for participants to complete outside the clinic, indicating its potential for widespread use.
  • Participants reported higher usability for ORCA-PD compared to MoCA, suggesting it may enhance patient engagement in cognitive assessments.
  • The ORCA-PD effectively distinguished between cognitively similar PD and NT groups, reinforcing its validity as a tailored assessment tool.
Interpretation:

The findings suggest that ORCA-PD is a promising tool for cognitive assessment in PD, addressing challenges of accessibility and specificity, which are critical for early detection and intervention.

Limitations:
  • The study included a relatively small sample size, which may affect generalizability and the robustness of findings.
  • Participants with PD had higher education levels than NT participants, which could influence cognitive performance and introduce bias.
Conclusion:

ORCA-PD shows potential as a valid and accessible cognitive screening tool for individuals with Parkinson's Disease, emphasizing the importance of overcoming barriers to cognitive assessment.

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