Unique Phase I NSCLC Trial Sites Decreasing in United States - Summary - MDSpire
Clinical Guidelines

Unique Phase I NSCLC Trial Sites Decreasing in United States

  • By

  • The ASCO Post Staff

  • May 12, 2026

  • 4 min

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A significant decline of 44% in unique clinical trial sites for non–small cell lung cancer (NSCLC) in the U.S. was observed from 2020 to 2024, indicating a trend toward consolidation at top-performing sites. This research, presented at the AACR Annual Meeting 2026, highlights rising concerns over site saturation, contradicting FDA calls for decentralizing trials. With 555 trials opened globally, the majority were in the U.S., where the number of active trial sites dropped from 395 to 223, affecting patient access to diverse clinical research.

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