Endovascular thrombectomy in patients with acute ischemic stroke and prestroke mRS 3: a multicenter IPTW analysis focused on functional preservation - Summary - MDSpire

Endovascular thrombectomy in patients with acute ischemic stroke and prestroke mRS 3: a multicenter IPTW analysis focused on functional preservation

  • By

  • Sangwon Choi

  • Minwoo Lee

  • Mi Sun Oh

  • Yerim Kim

  • Chulho Kim

  • Hee-Jin Im

  • Sang-Hwa Lee

  • May 22, 2026

  • 0 min

Share

Objective:

To evaluate the effectiveness and safety of reperfusion strategies in patients with acute ischemic stroke and prestroke disability (mRS score of 3).

Key Findings:
  • EVT was associated with a significantly higher likelihood of returning to prestroke functional status compared to MT (OR 7.63, 95% CI 3.02–19.28).
  • IVT showed no significant benefit in returning to prestroke functional status (OR 1.15, 95% CI 0.34–3.85).
  • EVT was associated with a favorable shift across the full mRS distribution (common OR 0.32, 95% CI 0.14–0.70).
  • Neither EVT nor IVT increased the risk of symptomatic hemorrhagic transformation or mortality.
Interpretation:

Limitations:
  • The study is observational and may be subject to biases inherent in such designs.
  • Patients selected for EVT may have more severe strokes, complicating direct comparisons with medically treated patients.
Conclusion:

Original Source(s)

Endovascular thrombectomy in patients with acute ischemic stroke and prestroke mRS 3: a multicenter IPTW analysis focused on functional preservation

  • by Sangwon Choi, Minwoo Lee, Mi Sun Oh, Yerim Kim, Chulho Kim, Hee-Jin Im, Sang-Hwa Lee

  • May 22, 2026

Related Content

Editorial: Diffusion-weighted imaging: advances and implementations in neurology

Prognostic significance of coagulation factor activity in acute stroke: a retrospective cohort study

Impaired pendulum-like mechanics during post-stroke walking: a biomechanical comparison with healthy individuals