Objective:

To analyze temporal trends and regional variation in the incidence of AA in Kazakhstan from 2014 to 2024.

Approach:

Key Findings:

• 1,209 incident cases of AA were identified during the study period.
• The median age of patients was 26 years, with a slight female predominance (52.3%).
• National incidence of AA increased from 0.21 per 100,000 in 2014 to 0.82 per 100,000 in 2024, primarily driven by idiopathic cases.
• 88.9% of cases were classified as idiopathic or unspecified.
• Regional variation observed, with the highest incidence in major urban centers (up to 1.48 per 100,000 in 2024).

Interpretation:

The increase in AA incidence in Kazakhstan is largely due to a rise in idiopathic cases.

Limitations:

• Limited data on the epidemiology of AA in Central Asia.
• Potential misclassification in diagnosis due to grouping of cases.

Conclusion:

The incidence of AA in Kazakhstan has increased over the past decade, primarily due to idiopathic cases, highlighting the need for improved surveillance and access to care.

Attribution Notice

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