To present a rare case of concurrent giant cell tumor of bone (GCTB) and enchondroma in the pubic bone, highlighting its histopathological characteristics and clinical implications in the context of existing literature.
Key Findings:
The coexistence of GCTB and enchondroma at the same anatomical site is exceedingly rare.
Histopathological analysis revealed GCTB with a Ki-67 proliferation index of 40%, indicating aggressive potential.
Immunohistochemical analysis confirmed the presence of H3.3 G34W mutation in GCTB.
Interpretation:
The case highlights the importance of histopathological assessment in diagnosing unusual tumor combinations and the potential for aggressive behavior in GCTB.
Limitations:
The rarity of concurrent GCTB and enchondroma limits the generalizability of findings.
Only two documented cases of this tumor combination exist in the literature.
Conclusion:
This case underscores the need for careful diagnostic evaluation in bone tumors and contributes to the understanding of rare tumor pairings.
