Objective:

To evaluate the effectiveness of peer support interventions in reducing fear of disease progression (FoP) and improving mental health in glioma patients.

Approach:

• Study Selection: Eight databases will be searched for eligible studies published until March 2026, focusing on peer support interventions for glioma patients.
• Quality Assessment: Methodological quality of selected studies will be independently evaluated by two reviewers.
• Data Analysis: Meta-analysis will be conducted using RevMan version 5.3 and Stata version 18.0 software.

Key Findings:

• Glioma patients experience high levels of fear of disease progression (FoP), which negatively impacts their quality of life.
• Peer support provides emotional, social, and practical assistance to patients.
• There is a lack of systematic reviews on the impact of peer support on FoP in glioma patients.

Interpretation:

The study aims to evaluate the effectiveness of peer support interventions in reducing FoP and improving mental health in glioma patients.

Limitations:

• The review is limited to studies published until March 2026.
• Only randomized controlled trials will be included, which may exclude relevant observational studies.

Conclusion:

The results will provide evidence regarding the effectiveness of peer support in addressing fear of disease progression in glioma patients.

Sources:

• Systematic Review Registration