What you see is not always what you get—MRI-based ganglionic eminence volumetry challenges subjective assessment in CNS anomalies - Summary - MDSpire

What you see is not always what you get—MRI-based ganglionic eminence volumetry challenges subjective assessment in CNS anomalies

  • By

  • Marlene Stuempflen

  • Patric Kienast

  • Victor U. Schmidbauer

  • Michael Weber

  • Athena Taymourtash

  • Johannes Tischer

  • Tim Dorittke

  • Julia Binder

  • Daniela Prayer

  • Gregor Kasprian

  • May 21, 2026

  • 0 min

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Objective:

To assess the ganglionic eminence (GE) in patients with structural CNS anomalies using quantitative fetal neuroimaging and to evaluate the feasibility of subjective assessments.

Approach:
    Key Findings:
    • Subjective assessment of the GE may miss subtle anomalies due to its changing shape and size.
    • Quantitative analysis using three-dimensional segmentation provides a more reliable assessment of the GE.
    Interpretation:

    Limitations:
    • Exclusion of patients with cystic or hemorrhagic alterations in the GE.
    • Control group included patients with minor structural anomalies, which may affect comparison.
    Conclusion:

Original Source(s)

What you see is not always what you get—MRI-based ganglionic eminence volumetry challenges subjective assessment in CNS anomalies

  • by Marlene Stuempflen, Patric Kienast, Victor U. Schmidbauer, Michael Weber, Athena Taymourtash, Johannes Tischer, Tim Dorittke, Julia Binder, Daniela Prayer, Gregor Kasprian

  • May 21, 2026

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