Evaluating the role of youth-onset diabetes mellitus in the context of food insecurity and preventive care: a repeated cross-sectional study using propensity score weighted machine learning analysis - Summary - MDSpire

Evaluating the role of youth-onset diabetes mellitus in the context of food insecurity and preventive care: a repeated cross-sectional study using propensity score weighted machine learning analysis

  • By

  • Yu-Sheng Lee

  • Raymond C Stetson

  • Heaven Hollender

  • Matthew Evan Sprong

  • Xueli Huang

  • Karan Kumar

  • Urja Nimitkumar Joshi

  • July 8, 2026

  • 0 min

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Objective:

To examine the association between food insecurity (FI) status and youth-onset diabetes mellitus (DM) among adolescents, and to evaluate the role of preventive care in this association.

Approach:
  • Study Design: Repeated cross-sectional analysis using data from the National Survey of Children’s Health (2016–2021).
  • Data Analysis: Propensity score weighting (PSW) was employed to balance confounders across FI groups, followed by logistic regression for variable selection and analysis.
Key Findings:
  • Moderate-to-severe FI was associated with higher odds of youth-onset DM (OR 1.55, 95% CI 1.35 to 1.77; p<0.0001).
  • Mild FI was not associated with youth-onset DM.
  • Among adolescents with preventive care visits, both mild FI (OR 1.19, 95% CI 1.04 to 1.37; p=0.0126) and moderate-to-severe FI (OR 1.67, 95% CI 1.46 to 1.92; p<0.0001) were linked to higher odds of DM.
  • Among those without preventive care visits, moderate-to-severe FI was associated with lower odds of reported DM diagnosis (OR 0.11, 95% CI 0.03 to 0.35; p=0.0002).
Interpretation:

The relationship between FI and youth-onset DM varies based on access to preventive care, indicating that adolescents with FI lacking regular preventive care may have fewer opportunities for DM diagnosis.

Limitations:
  • The study relies on self-reported data, which may introduce reporting bias.
  • The cross-sectional design limits causal inferences.
Conclusion:

Moderate-to-severe FI is associated with youth-onset DM, and access to preventive care influences the detection of diabetes in adolescents.

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