Objective:

To describe the multidisciplinary team (MDT) management, treatment strategies, and outcomes of patients with abdominal vascular graft and endograft infections (aVGEI) in Eastern Denmark.

Approach:

• Study Design: A retrospective cohort study of patients diagnosed with aVGEI between July 1, 2022, and June 30, 2025, discussed at an MDT conference.
• Patient Inclusion: Patients suspected of aVGEI were evaluated at the MDT conference, with only the first instance of infection included in the analysis.
• Outcome Measures: The primary outcome was 90-day mortality; secondary outcomes included cure, remission, treatment failure at one year, and re-hospitalization.

Key Findings:

• VGEI are rare but pose significant diagnostic and therapeutic challenges.
• Diagnosis relies on clinical, laboratory, and radiological evaluations, often requiring MDT involvement.
• No standardized regimen for empirical antibiotic treatment exists, necessitating individualized strategies.

Interpretation:

The study highlights the complexity of managing aVGEI and the importance of a standardized MDT approach for diagnosis and treatment.

Limitations:

• Absence of randomized controlled trials and limited larger cohort studies.
• Data is specific to Eastern Denmark and may not be generalizable.

Conclusion:

The study provides insights into the management and outcomes of aVGEI, emphasizing the need for standardized approaches.

Sources:

• MAGIC criteria