Non-occlusive mesenteric ischemia complicated by ischemic hepatitis presenting as severe lactic acidosis: a case report - Summary - MDSpire

Severe Lactic Acidosis Due to Non-occlusive Mesenteric Ischemia and Ischemic Hepatitis: A Case Study

  • By

  • Huan Geng

  • Hui Ye

  • Ming Lei

  • July 20, 2026

Share

Objective:

To report a case of severe lactic acidosis resulting from non-occlusive mesenteric ischemia (NOMI) and ischemic hepatitis (IH) in an elderly patient.

Approach:
  • Case Presentation: An 84-year-old man with a history of panvascular disease developed severe lactic acidosis after foot surgery, leading to ICU admission and multidisciplinary management.
Key Findings:
  • The patient exhibited marked hyperlactatemia with lactate levels exceeding 20 mmol/L.
  • Imaging revealed extensive atherosclerosis of the abdominal aorta and its branches, mural thrombi, penetrating atherosclerotic ulcers, and ischemic changes in the bowel and right hepatic lobe.
  • NOMI and IH were diagnosed as complications of splanchnic hypoperfusion.
Interpretation:

NOMI should be considered in elderly patients with panvascular disease presenting with unexplained hyperlactatemia and metabolic acidosis.

Limitations:
  • The case study is based on a single patient, limiting generalizability.
  • Lack of long-term follow-up data on the patient's recovery.
Conclusion:

NOMI and ischemic hepatitis are severe complications that require early recognition and multidisciplinary management.

Original Source(s)

Related Content