Objective:

To evaluate early and mid-term outcomes after lung transplantation using lungs from polytrauma donors (PD) compared with non-polytrauma donors (NPD).

Approach:

Key Findings:

• PDs were younger and more frequently male, with a higher prevalence of pulmonary contusions.
• Early postoperative outcomes, including PGD, ICU stay, and perioperative complications, were comparable between groups.
• At 6 months, overall survival was higher in the PD group (91.7% vs. 75.3%, p = 0.048).
• After PSM, no significant differences were observed in survival (p = 0.66), perioperative outcomes, or pulmonary function.

Interpretation:

Lung transplantation using grafts from polytrauma donors is not associated with worse perioperative or mid-term outcomes. After adjustment for baseline differences, outcomes were comparable to those from non-polytrauma donors.

Limitations:

• Retrospective design may introduce bias.
• Exclusion of donors after circulatory death and those who died during surgery may limit generalizability.

Conclusion:

Outcomes from lung transplantation using polytrauma donor grafts support their safe and selective use to expand the donor pool.

Attribution Notice

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