Bilateral Acute Angle Closure as an Uncommon Presentation of Relapsing Polychondritis: A Diagnostic Dilemma - Summary - MDSpire

Bilateral Acute Angle Closure as an Uncommon Presentation of Relapsing Polychondritis: A Diagnostic Dilemma

  • By

  • Vipin Rana

  • Vikas Sharma

  • Sandepan Bandopadhyay

  • Santosh Kumar

  • Sonali Vinay Kumar

  • December 3, 2025

  • 0 min

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Objective:

To report a rare case of bilateral angle-closure glaucoma as the initial manifestation of relapsing polychondritis (RP) and discuss the significant diagnostic challenges involved.

Key Findings:
  • Bilateral angle-closure glaucoma can be an initial presentation of relapsing polychondritis, highlighting the need for awareness.
  • Systemic signs such as fever and sensorineural hearing loss may precede classical symptoms of RP, complicating diagnosis.
  • Diagnosis of RP was confirmed using the Modified Michet criteria after ruling out other conditions.
Interpretation:

This case emphasizes the need for clinicians to consider relapsing polychondritis in patients presenting with unexplained bilateral angle-closure glaucoma and systemic inflammatory symptoms, to facilitate timely diagnosis.

Limitations:
  • The rarity of the condition limits generalizability of findings and may lead to misdiagnosis.
  • The absence of classical signs of RP may delay diagnosis.
Conclusion:

Bilateral angle-closure glaucoma can serve as an atypical presentation of relapsing polychondritis, necessitating a high index of suspicion for timely diagnosis and management in clinical practice.

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