To assess the risk factors for progression to septic shock in patients with obstructive acute pyelonephritis associated with upper urinary calculi, highlighting the significance of these factors for improving patient outcomes.
Key Findings:
Median age of patients was 67 years with a male/female ratio of 0.53, indicating a potential demographic trend.
32.7% of patients had poor performance status (2-4), which may correlate with higher risk.
Underlying diseases included diabetes mellitus (DM), cardiovascular or neurologic diseases, and immunocompromised status, suggesting a need for targeted management.
68.1% of patients showed significant leukocyte count shifts, indicating a potential marker for septic progression.
Interpretation:
The study highlights the importance of identifying risk factors for septic shock in patients with obstructive acute pyelonephritis to improve management and outcomes.
Limitations:
Retrospective design may introduce bias, and the exclusion of patients undergoing surgical intervention could limit generalizability and affect the applicability of findings.
Conclusion:
Identifying predictors of septic shock in obstructive acute pyelonephritis can aid in timely intervention, potentially reducing morbidity and mortality, emphasizing the need for prompt clinical action.
