Objective:

To provide direct clinicopathological evidence of a recognizable pre-perforating stage in acquired reactive perforating collagenosis (ARPC).

Approach:

Key Findings:

• Early lesions of ARPC can be identified with specific dermoscopic features distinct from fully developed lesions.
• Histopathological examination of early lesions shows abnormal collagen organization without transepidermal elimination.
• The study provides evidence for a definable pre-perforating stage in ARPC.

Interpretation:

Limitations:

• The study is based on a single case report, limiting generalizability.
• Further research is needed to confirm findings across a larger population.

Conclusion:

The findings support the existence of a pre-perforating stage in ARPC.

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