Incidence and Burden of Respiratory Syncytial Virus-Associated Hospitalizations Among People 65 and Older in France: A National Hospital Database Study - Summary - MDSpire

Incidence and Burden of Respiratory Syncytial Virus-Associated Hospitalizations Among People 65 and Older in France: A National Hospital Database Study

  • By

  • Stéphane Marot

  • Clarisse Demont

  • Théophile Cocherie

  • Miao Jiang

  • Charlotte Charpentier

  • Andre Araujo

  • Tianyi Lu

  • Mathieu Uhart

  • Nadia El Mouaddin

  • Magali Lemaitre

  • Sophie Larrieu

  • Clélia Bignon-Favary

  • Emilie Lambourg

  • Arnaud Cheret

  • David Martin

  • Anne-Geneviève Marcelin

  • Diane Descamps

  • Vincent Calvez

  • Quentin Le Hingrat

  • September 15, 2025

  • 0 min

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Objective:

To estimate national-level RSV hospitalization rates and examine the clinical and economic burden in high-risk elderly populations in France, specifically those with chronic conditions.

Key Findings:
  • Adjusted incidence of RSV hospitalizations for adults aged 75+ ranged from 85 to 221 per 100,000, with significant ICU admissions contributing to the overall burden.
  • Inpatient mortality rates were between 8.9% and 10.4%.
  • Annual adjusted costs of RSV hospitalizations ranged from €27 to €76 million, with significant ICU admissions.
  • High-risk adults aged 65–74 had higher adjusted incidence rates of 161–735 per 100,000.
Interpretation:

The burden of RSV on older adults, particularly those with chronic conditions, is substantial and often underreported, highlighting the need for improved diagnostics and vaccination strategies to inform public health policy.

Limitations:
  • Underreporting of RSV cases due to diagnostic challenges and lack of standardized testing.
  • Potential misclassification of severe RSV cases due to secondary infections or exacerbation of chronic conditions, which may affect the accuracy of the findings.
Conclusion:

Enhanced diagnostics and targeted vaccination programs are essential to mitigate the impact of RSV on vulnerable elderly populations, urging healthcare providers to prioritize vaccination efforts.

Original Source(s)

Incidence and Burden of Respiratory Syncytial Virus-Associated Hospitalizations Among People 65 and Older in France: A National Hospital Database Study

  • by Stéphane Marot, Clarisse Demont, Théophile Cocherie, Miao Jiang, Charlotte Charpentier, Andre Araujo, Tianyi Lu, Mathieu Uhart, Nadia El Mouaddin, Magali Lemaitre, Sophie Larrieu, Clélia Bignon-Favary, Emilie Lambourg, Arnaud Cheret, David Martin, Anne-Geneviève Marcelin, Diane Descamps, Vincent Calvez, Quentin Le Hingrat

  • September 15, 2025

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