Clinical Outcomes of SMILE, Femtosecond LASIK, and Transepithelial PRK: A Multicenter Study in Iraq - Summary - MDSpire

Clinical Outcomes of SMILE, Femtosecond LASIK, and Transepithelial PRK: A Multicenter Study in Iraq

  • By

  • Hassan A. Aljaberi

  • Saeed Rahmani

  • Humam H. Alrikabi

  • April 14, 2026

  • 0 min

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Objective:

To compare refractive predictability, long-term stability, visual quality, ocular surface outcomes, and safety of SMILE, FS-LASIK, and Trans-PRK for myopia correction in an Iraqi population over a specified time frame.

Key Findings:
  • SMILE showed the highest refractive predictability and long-term stability, with specific data points to be included.
  • FS-LASIK had intermediate outcomes, while Trans-PRK had greater residual myopia and increased refractive regression.
  • Induced corneal HOAs were lowest after SMILE and highest after Trans-PRK.
  • OSDI scores were lowest after SMILE, intermediate after FS-LASIK, and highest after Trans-PRK.
  • Surgical technique was the primary predictor of residual SE at 1.5 years.
Interpretation:

SMILE is superior in refractive predictability, stability, visual quality, and ocular surface outcomes compared to FS-LASIK and Trans-PRK, suggesting the need for procedure-specific patient selection to optimize outcomes.

Limitations:
  • Retrospective design may introduce selection bias; further context on its impact on results is needed.
  • Long-term follow-up beyond 1.5 years is needed for comprehensive assessment.
Conclusion:

SMILE is the preferred method for myopia correction in this cohort, while FS-LASIK remains effective and safe. Trans-PRK is less favorable due to greater refractive regression and higher enhancement rates, highlighting the importance of these findings in the context of global myopia trends.

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