Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort - Summary - MDSpire

Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort

  • By

  • Laura Pina Vegas

  • Miranda van Lunteren

  • Damien Loeuille

  • Caroline Morizot

  • Esther Newsum

  • Sofia Ramiro

  • Floris van Gaalen

  • Alain Saraux

  • Pascal Claudepierre

  • Antoine Feydy

  • Désirée van der Heijde

  • Monique Reijnierse

  • March 6, 2025

  • 0 min

Share

Objective:

To report the occurrence of degenerative spinal lesions over 10 years in young patients with axSpA and assess the change of these lesions and associated factors, including demographic and clinical variables.

Key Findings:
  • High initial prevalence of degenerative lesions in axSpA patients, with nearly 30% on radiographs and over 70% on MRI at baseline, indicating a need for targeted management strategies.
  • The evolution of degenerative lesions over 10 years remains poorly documented, highlighting the necessity for further investigation into their progression and clinical implications.
Interpretation:

The presence and progression of degenerative spinal lesions in axSpA patients could significantly influence diagnosis and management, underscoring the importance of long-term monitoring for optimal patient outcomes.

Limitations:
  • Some patients were withdrawn from the study if they were not considered to have axSpA during follow-up, which may affect the generalizability of the findings.
  • The study may not fully capture the variability in lesion progression due to the limited number of imaging time points.
Conclusion:

Understanding the long-term evolution of degenerative spinal lesions in axSpA is crucial for improving patient management and treatment strategies.

Original Source(s)

Related Content