To report a case of hair repigmentation and regrowth during baricitinib treatment in a patient with canities subita and concurrent alopecia areata.
Approach:
Key Findings:
Complete hair repopulation occurred along with resolution of the alopecic patch.
Hair regrowth was denser and grayer rather than returning to baseline pigmentation.
No adverse events were reported, and rheumatoid arthritis remained in remission.
Interpretation:
The case supports a potential link between canities subita and alopecia areata, but does not establish baricitinib as an effective treatment for canities subita.
Limitations:
Single-patient case report design without a comparator group.
Lack of standardized alopecia severity or pigmentation outcomes.
Clinical diagnosis made without histopathologic confirmation.
Concurrent withdrawal of etanercept may have confounded results.
Conclusion:
The report should not be interpreted as establishing baricitinib as an effective treatment for canities subita, and its use would be off-label.
