Upgrading Housing-First Interventions in the Age of Fentanyl - Summary - MDSpire

Upgrading Housing-First Interventions in the Age of Fentanyl

  • By

  • Karen Drexler

  • May 5, 2026

  • 0 min

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Objective:

To evaluate the effectiveness of housing-first strategies for individuals with opioid use disorder (OUD) in the context of the urgent fentanyl crisis.

Key Findings:
  • Only 17% of PEH with OUD in HUD-VASH received MOUD within the first 12 months, highlighting a critical gap in care.
  • Lower MOUD receipt was noted among racial and ethnic minority veterans and those admitted to inpatient care, indicating disparities in access.
  • Increased odds of MOUD receipt were associated with diagnoses of depression, frequent mental health visits, and substance use disorder treatment encounters, suggesting areas for intervention.
Interpretation:

The findings suggest that noncontingent housing-first models may not provide adequate care for individuals with OUD, especially in the context of the fentanyl crisis, where overdose risks are heightened, necessitating policy reevaluation.

Limitations:
  • The study's observational nature limits causal inferences, which may affect the generalizability of the findings.
  • The sample may not be representative of all PEH with OUD, potentially skewing the results.
Conclusion:

Housing-first strategies must be integrated with robust MOUD provision to enhance survival and quality of life for individuals with OUD, particularly in the fentanyl era, necessitating immediate action.

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