Objective:

To systematically synthesise the evidence behind the use of narrow band imaging (NBI) and acetic acid chromoendoscopy (AAC) in Barrett’s oesophagus (BO) surveillance.

Approach:

Key Findings:

• NBI-targeted biopsies are more effective in overall dysplasia detection than white light endoscopy (WLE).
• AAC demonstrated a higher sensitivity for neoplasia detection than WLE.
• Neither NBI-guided nor AAC-guided biopsy can replace the Seattle protocol.

Interpretation:

NBI provides higher dysplasia detection and AAC has a higher sensitivity, but neither can safely replace Seattle protocol biopsies.

Limitations:

• The review included only peer-reviewed full publications, excluding observational studies and non-English publications. The findings are based on the synthesis of existing studies, which may have varying quality.

Conclusion:

This review highlights the need for high-quality randomized controlled trials on advanced imaging techniques in BO surveillance.

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