Elevated angiography-derived microvascular resistance and HbA1c levels jointly predict adverse outcomes in patients with diabetic STEMI: a multicenter retrospective cohort study - Summary - MDSpire

Elevated angiography-derived microvascular resistance and HbA1c levels jointly predict adverse outcomes in patients with diabetic STEMI: a multicenter retrospective cohort study

  • By

  • Shiyi Gao

  • Yu Wang

  • Jun Wang

  • Qiang Zeng

  • Zengwei Cheng

  • Zichen Han

  • Hongju Wang

  • Miaonan Li

  • Sigan Hu

  • June 22, 2026

  • 0 min

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Objective:

To investigate the combined prognostic value of post-PCI AMR and HbA1c levels for MACCEs in patients with STEMI and T2DM.

Approach:
    Key Findings:
    • HbA1c (HR = 1.403) and AMR (HR = 1.213) were independently associated with MACCEs.
    • Patients with HbA1c ≥6.5% and AMR ≥250.5 mmHg·s/m had the highest risk of MACCEs (HR = 6.903).
    • Nonlinear relationships were observed between MACCEs and both HbA1c and AMR levels.
    Interpretation:

    Limitations:
    • Retrospective design may introduce selection bias.
    • Limited generalizability due to specific inclusion criteria.
    Conclusion:

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