To investigate the agreement between two spectral-domain OCT devices, the Heidelberg Spectralis and Zeiss Cirrus 6000, in measuring peripapillary RNFL thickness, maximal disc height, and macular ganglion cell layer in individuals with idiopathic intracranial hypertension (IIH).
Approach:
Participants: Eligible participants were adults with a definite IIH diagnosis attending a neuro-ophthalmology outpatient clinic, with data collected from the IIH:Life registry.
Data Collection: Data included age, sex, lumbar puncture opening pressure, body mass index, and disease duration.
OCT Imaging: Participants underwent same-day spectral-domain OCT imaging using both Spectralis and Cirrus devices, measuring RNFL thickness, maximum disc height, and GCL volume.
Key Findings:
The study aimed to assess the agreement of OCT measurements across different devices in patients with IIH.
Measurements included global RNFL thickness, maximum disc height, and GCL volume.
Limitations:
The study was conducted at a single center, which may limit generalizability.
The sample size and demographic diversity were not detailed in the provided context.
by Gabriele Berman, Andreas Yiangou, Mark Thaller, Nick Capewell, Donna Holding, Georgios Tsermoulas, Alexandra J. Sinclair, Richard J. Blanch, Susan P. Mollan
