To investigate if detrusor overactivity (DO) in patients with urodynamic-confirmed benign prostatic obstruction (BPO) alters urodynamic parameters.
Key Findings:
Significant differences in maximum cystometric capacity (MCC) and bladder compliance (BC) between BPO with DO (MCC: 259.05 ± 44.54, BC: 158.71 ± 83.86) and BPO without DO (MCC: 273.13 ± 36.69, BC: 210.95 ± 82.58).
BPO with TDO showed more pronounced storage-phase changes compared to BPO with PDO (MCC: 291.50 vs. 250.00, BC: 184.00 vs. 103.00).
Age was identified as an independent risk factor for DO (OR = 1.19, p < 0.001), while first desire to void (FD) was a protective factor (OR = 0.98, p < 0.001).
Interpretation:
DO is associated with significant storage-phase urodynamic alterations in BPO patients, with TDO linked to more pronounced changes than PDO, suggesting potential implications for treatment strategies.
Limitations:
Several comparisons remain unadjusted, particularly regarding the correlation analyses, making findings exploratory.
Conclusion:
Future prospective studies with larger samples and age-adjusted designs are essential to validate these findings and explore their clinical implications.
