Using objective measures of physical activity, sleep, and breathing for disease profiling of patients with systemic lupus erythematosus and Sjögren's disease - Summary - MDSpire
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Using objective measures of physical activity, sleep, and breathing for disease profiling of patients with systemic lupus erythematosus and Sjögren's disease
To evaluate passive sensing for identifying activity, sleep, and breathing patterns that distinguish SLE and SjD phenotypes in the home environment.
Key Findings:
SLE participants exhibited lower physical activity, poorer sleep quality, and higher breathing rate and variability compared to healthy participants.
SjD participants showed reduced physical activity but no significant differences in sleep and breathing compared to healthy controls.
Digital measurements had weak correlation with self-reported symptoms, but higher breathing rate and variability were associated with higher SLE disease activity.
Interpretation:
Limitations:
The study's sample size may limit the generalizability of the findings.
The reliance on digital measures may not fully capture the complexity of symptoms experienced by patients.
