Mesonephric-like adenocarcinoma as an unexpected histological result after fertility saving procedure for presumed adenomyosis: a case report - Summary - MDSpire

Mesonephric-like adenocarcinoma as an unexpected histological result after fertility saving procedure for presumed adenomyosis: a case report

  • By

  • Vojtěch Lukavec

  • Filip Frühauf

  • Zdenka Lisa

  • Jan Galko

  • Pavel Dundr

  • Michal Mara

  • June 5, 2026

  • 0 min

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Objective:

To raise clinical awareness about the risk of misdiagnosing an unexpected malignancy that can mimic diffuse adenomyosis.

Key Findings:
  • Mesonephric-like adenocarcinoma can mimic diffuse adenomyosis on imaging.
  • The patient had a significant tumor size (5 x 6 cm) and was diagnosed at an advanced disease stage.
  • Histopathological evaluation is crucial for atypical myometrial lesions to prevent misdiagnosis.
Interpretation:

This case emphasizes the need for a comprehensive evaluation of atypical myometrial lesions, including imaging and histopathological assessment, to avoid misdiagnosis.

Limitations:
  • The rarity of mesonephric-like adenocarcinoma may limit generalizability to broader populations.
  • The case is based on a single patient experience, which may not reflect the wider clinical context.
Conclusion:

Thorough evaluation of atypical myometrial lesions is essential, especially in patients with fertility concerns, to ensure accurate diagnosis and appropriate management.

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