To explore the imaging features of histopathologically confirmed ovarian Brenner tumors (BTs) and to enhance the accuracy of differential diagnosis between benign and borderline or malignant variants, which is crucial for patient management.
Key Findings:
Elevated serum CA125 levels were significantly greater in the borderline/malignant group compared to the benign group (p < 0.05).
Significant differences in imaging characteristics were found between benign and malignant tumors, including maximum tumor diameter, tumor composition, tumor margin, presence of papillary projections, calcification pattern, degree of enhancement, and CT attenuation values (p < 0.05).
Tumor maximum diameter, papillary projections, and venous-phase CT net enhancement were identified as independent risk factors for borderline/malignant BTs.
The combined model showed promising discriminative ability with an AUC of 0.956, indicating high accuracy.
Interpretation:
Maximum tumor diameter, presence of papillary projections, and venous-phase CT net enhancement are valuable markers for differentiating benign from borderline or malignant subtypes, which can significantly impact preoperative decision-making.
Limitations:
The study is retrospective and may have inherent biases that could affect the generalizability of the findings.
The sample size is limited to 55 BT lesions from 52 patients, which may not fully represent the diversity of BT presentations.
Conclusion:
These imaging features may assist in preoperative imaging assessment and risk categorization, ultimately improving patient outcomes.
