Affiliate stigma and health-related quality of life among caregivers of people with severe mental illness in a collectivist context: a cross-sectional study - Summary - MDSpire

Affiliate stigma and health-related quality of life among caregivers of people with severe mental illness in a collectivist context: a cross-sectional study

  • By

  • Peng Fu

  • Ziyi Xiong

  • Yang Liu

  • Yong Li

  • Lian Yang

  • June 12, 2026

  • 0 min

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Objective:

To examine the level of affiliate stigma and its association with specific aspects of health-related quality of life (HRQoL) among primary caregivers of individuals with severe mental disorders.

Approach:
    Key Findings:
    • Mean affiliate stigma score among caregivers was 48.67 ± 15.63.
    • Mean EQ-5D utility index was 0.95 ± 0.07.
    • Mean Visual Analog Scale self-rated health score was 70.48 ± 17.22.
    • HRQoL was significantly associated with age, income, gender, educational level, and occupational status (p < 0.05).
    • Affiliate stigma was a significant negative predictor of caregiver HRQoL (EQ-5D-3L: β = -0.0032, p < 0.001; EQ-VAS: β = -0.3175, p < 0.001).
    • Female caregivers had significantly lower utility index scores (p < 0.05).
    • Lower income was significantly associated with lower self-rated health scores (p < 0.001).
    Interpretation:

    The study demonstrated a significant negative association between affiliate stigma and HRQoL among primary caregivers of individuals with severe mental disorders.

    Limitations:
    • Limited local evidence regarding the interrelationship between affiliate stigma and HRQoL, which may affect the generalizability of the findings.
    • Most existing studies conducted in Western individualistic cultural contexts may not be applicable to collectivist societies like China, potentially limiting the understanding of stigma in this context.
    Conclusion:

    The findings highlight the need for targeted interventions to reduce affiliate stigma and improve the health-related quality of life of caregivers, suggesting avenues for future research and practice.

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