To systematically compare outcomes between patients undergoing prophylactic clip closure and those not undergoing closure after EMR for esophageal SMTs.
Approach:
Study Design: Retrospective cohort study conducted at Shenzhen Hospital of Southern Medical University.
Patient Selection: Consecutive patients diagnosed with esophageal SMTs who underwent EMR were included based on specific inclusion and exclusion criteria.
Intervention: Patients were divided into two groups: closure group (metal clips applied post-EMR) and non-closure group (no clips, routine observation).
Data Collection: Data on patient characteristics, lesion characteristics, perioperative data, and postoperative complications were collected.
Statistical Analysis: Statistical analysis was performed using SPSS software, with appropriate tests for continuous and categorical variables.
Key Findings:
The study included 84 patients, with 52 in the closure group and 32 in the non-closure group.
Data on hospital stay duration and medical costs were also assessed.
Interpretation:
The clinical necessity, efficacy, and safety of routine prophylactic clip closure following EMR for esophageal SMTs remain inadequately defined due to a lack of high-level evidence.
Limitations:
Limited data on esophageal lesions compared to other gastrointestinal lesions.
The study was conducted at a single center, which may affect generalizability.
