Urban Exposome and Skin Microbiome in Atopic Dermatitis: A Comparative Study Between Two Brazilian Municipalities - Summary - MDSpire
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Comparative Analysis of Urban Exposome and Skin Microbiome in Atopic Dermatitis Across Two Brazilian Cities

  • By

  • Heloísa Silva de Avó Freixo

  • Hélio Amante Miot

  • Marília Marufuji Ogawa

  • Ivanka Miranda de Castro Martins

  • Vânia Rodrigues Leite e Silva

  • Newton Andreo Filho

  • Patrícia Santos Lopes

  • Romualdo Morandi Filho

  • Ediléia Bagatin

  • September 17, 2026

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Objective:

To compare the skin microbiome of patients with atopic dermatitis (AD) from two municipalities in São Paulo State, Brazil, differing in urban exposome exposure.

Approach:
  • Study Design: Cross-sectional comparative investigation involving ten children and ten adults with active AD from a metropolitan area and a less polluted interior municipality.
  • Sample Collection: Skin microbiome specimens were collected from eczematous lesions in the antecubital or popliteal fossae.
Key Findings:
  • No differences in overall bacterial diversity were observed between municipalities or age groups.
  • Patients from the metropolitan municipality showed significantly greater relative abundance of Staphylococcus aureus.
Limitations:
  • The study did not include paired simultaneous ambient concentration measurements from both municipalities.
  • The sample size was limited to twenty participants.

Original Source(s)

Urban Exposome and Skin Microbiome in Atopic Dermatitis: A Comparative Study Between Two Brazilian Municipalities

  • by Heloísa Silva de Avó Freixo, Hélio Amante Miot, Marília Marufuji Ogawa, Ivanka Miranda de Castro Martins, Vânia Rodrigues Leite e Silva, Newton Andreo Filho, Patrícia Santos Lopes, Romualdo Morandi Filho, Ediléia Bagatin

  • September 17, 2026

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