Effect of biofeedback electrical stimulation combined with HoLEP on surgical outcomes in patients with benign prostatic hyperplasia complicated with detrusor underactivity: a retrospective cohort study - Summary - MDSpire

Effect of biofeedback electrical stimulation combined with HoLEP on surgical outcomes in patients with benign prostatic hyperplasia complicated with detrusor underactivity: a retrospective cohort study

  • By

  • Tengfei Gu

  • Jie Li

  • Ting Chen

  • Yongtao Pan

  • Qinzhou Yu

  • Jing Sha

  • May 25, 2026

  • 0 min

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Objective:

To investigate the clinical efficacy and safety of biofeedback electrical stimulation combined with holmium laser enucleation of the prostate (HoLEP) in the treatment of patients with benign prostatic hyperplasia (BPH) complicated by detrusor underactivity (DUA) from January 2023 to June 2025.

Key Findings:
  • Intervention group had significantly higher Qmax (14.38 mL/s vs. 10.01 mL/s, P < 0.001) and BCI (111.68 vs. 93.96, P < 0.001) at 3 months postoperatively, with all results indicating statistical significance.
Interpretation:

Biofeedback electrical stimulation combined with HoLEP significantly improves voiding function, clinical symptoms, and quality of life in patients with BPH and DUA, enhances bladder contractility, and reduces the risk of postoperative complications, suggesting a need for broader clinical adoption.

Limitations:
  • Retrospective design may introduce selection bias, and limited generalizability due to single-center study may affect the applicability of the findings.
Conclusion:

Biofeedback electrical stimulation combined with HoLEP offers clinical benefits and a favorable safety profile for patients with BPH and DUA, warranting further investigation and consideration in treatment protocols.

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