Stigma and quality of life in hospitalized schizophrenia patient-family caregiver dyads in Northern China: an actor-partner interdependence model analysis - Summary - MDSpire

Stigma and quality of life in hospitalized schizophrenia patient-family caregiver dyads in Northern China: an actor-partner interdependence model analysis

  • By

  • Kang Xie

  • Honglei Yang

  • Xinyi Ge

  • Qunshan Wang

  • Zhenyue Liu

  • Xianyun Li

  • Botao Ma

  • June 30, 2026

  • 0 min

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Objective:

To systematically analyze the dyadic associations of stigma experienced by both patients with schizophrenia and their family caregivers with quality of life (QoL), utilizing an actor-partner interdependence model (APIM).

Approach:
  • Participants: Two hundred and sixty-four pairs of schizophrenic patients and their family caregivers were included in the study.
  • Measurement: Stigma was measured using the Internalized Stigma of Mental Illness Scale and the Conjunctive Stigma Scale, while QoL was measured using the World Health Organization Quality of Life Measurement Short Form.
  • Model: The actor-partner reciprocity model was constructed to explore the actor and partner effects of stigma on QoL.
Key Findings:
  • The actor effect of stigma on QoL was significant for patients (β=-0.472, p < 0.001) and caregivers (β=-0.779, p < 0.001).
  • The partner effect of stigma on QoL was significant for patients (β=-0.128, p = 0.033) and caregivers (β=-0.419, p < 0.001).
Interpretation:

The study examines the interdependence of stigma between patients and caregivers and its correlation with their quality of life.

Limitations:
  • The study is limited to a specific population of hospitalized individuals in Northern China, which may affect generalizability.
  • The cross-sectional design does not allow for causal inferences.
Conclusion:

Future research should consider both individual and partner stigma in relation to quality of life for patients and caregivers.

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