Objective:

To report a case of post-cerebral hemorrhage depressive disorder complicated by obstructive sleep apnea hypopnea syndrome (OSAHS) and rapid eye movement sleep behavior disorder (RBD).

Approach:

• Case Report: A 63-year-old male with post-cerebral hemorrhage depression underwent polysomnography (PSG) and was treated for OSAHS and RBD, leading to improvement in depressive symptoms.

Key Findings:

• The patient had severe OSAHS and RBD, which were identified through detailed history and PSG.
• Initial antidepressant treatment was ineffective, but subsequent CPAP therapy for OSAHS and targeted pharmacotherapy for RBD resulted in significant improvement in mood and daytime function.

Interpretation:

The findings suggest that for patients with post-stroke depression unresponsive to standard antidepressant treatments, evaluating and managing comorbid sleep disorders may enhance treatment efficacy.

Limitations:

• The study is based on a single case report, limiting generalizability.
• Long-term outcomes and the effectiveness of the interventions beyond the immediate treatment period are not discussed.

Conclusion:

Identifying and treating sleep disorders in patients with post-stroke depression may be crucial.