To evaluate the 2-year outcomes of trabeculo-canalectomy in Chinese patients with glaucoma secondary to iridocorneal endothelial syndrome (GS-ICE).
Approach:
Study Design: Retrospective study involving 26 GS-ICE patients treated with trabeculo-canalectomy and followed for 2 years, with outcomes assessed at multiple follow-up visits.
Surgical Procedure: Trabeculo-canalectomy performed without antimetabolites by the same experienced surgeon, following a standardized protocol.
Key Findings:
Postoperative mean IOP significantly reduced from 31.10 ± 11.00 mmHg preoperatively to 13.27 ± 2.68 mmHg at 1 week and remained lower at subsequent follow-ups (p < 0.001).
The number of postoperative anti-glaucoma medications decreased significantly, reaching 0 at all follow-up visits (p < 0.001).
Complete success rate at 2 years was 80.8% (p < 0.001), while conditional success was 11.5%.
Hyphema was the most common early complication (7.7%), self-resolving within the first week.
Interpretation:
Trabeculo-canalectomy demonstrates favorable outcomes in controlling IOP and reducing medication needs in GS-ICE patients over a 2-year period.
Limitations:
Retrospective design may introduce selection bias.
Small sample size of 26 patients limits generalizability.
Conclusion:
Trabeculo-canalectomy provides effective IOP control and reduces the need for anti-glaucoma medications with a low complication rate in GS-ICE patients over a 2-year period.
