Spontaneous Coronary Artery Dissection in an Underrepresented Region: Insights from the Serbian (RS) SCAD Registry - Summary - MDSpire

Spontaneous Coronary Artery Dissection in an Underrepresented Region: Insights from the Serbian (RS) SCAD Registry

  • By

  • Apostolović, Svetlana Radomir

  • Stanojevic, Dragana

  • Mehmedbegovic, Zlatko

  • Krljanac, Gordana

  • Ilić, Ivan

  • Petrovic, Milovan

  • Djokovic, Aleksandra

  • Mitov, Vladimir

  • Zdravkovic, Vladimir

  • Kovacevic, Mila

  • Maricic, Bojan

  • Andjelkovic Apostolovic, Marija

  • Nikolic, Miroslav

  • Cankovic, Milenko

  • Dabovic, Dragana

  • Zivanovic, Zeljko

  • Stanetic, Bojan

  • Iveljic, Ivana

  • Nikolic, Dusan

  • Aleksandric, Srdjan

  • Beleslin, Branko Dusan

  • April 24, 2026

  • 0 min

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Objective:

To provide comprehensive multicenter data on spontaneous coronary artery dissection (SCAD) from the Serbian SCAD Registry, highlighting significant differences from Western cohorts that may impact clinical management.

Key Findings:
  • Among 123 patients, the mean age was 47.8 years, with 85.4% being female.
  • High prevalence of traditional cardiovascular risk factors: hypertension (49.6%), dyslipidemia (46.3%), smoking (41.5%).
  • Emotional stress was the most common precipitating factor (38.5%).
  • Left anterior descending artery involvement occurred in 56.1%, with Type 2a SCAD being the most frequent (42.1%).
  • PCI was performed in 51.3%, and dual antiplatelet therapy was prescribed in 87%.
  • In-hospital MACE occurred in 23.6%, with mortality at 8.1%.
  • One-year MACE was 8.2%.
Interpretation:

The Serbian SCAD cohort exhibits a distinct profile with a higher burden of cardiovascular risk factors and adverse events compared to Western registries, suggesting a need for improved management strategies that could enhance patient outcomes.

Limitations:
  • Data primarily derived from a single region may limit generalizability to other populations.
  • Follow-up duration may not capture long-term outcomes comprehensively, potentially underestimating the true incidence of adverse events.
Conclusion:

The findings indicate that greater adherence to guideline-based conservative management may improve outcomes for SCAD patients in Eastern Europe, highlighting the need for tailored approaches in this demographic.

Original Source(s)

Spontaneous Coronary Artery Dissection in an Underrepresented Region: Insights from the Serbian (RS) SCAD Registry

  • by Apostolović, Svetlana Radomir, Stanojevic, Dragana , Mehmedbegovic, Zlatko , Krljanac, Gordana , Ilić, Ivan , Petrovic, Milovan , Djokovic, Aleksandra , Mitov, Vladimir , Zdravkovic, Vladimir , Kovacevic, Mila , Maricic, Bojan , Andjelkovic Apostolovic, Marija , Nikolic, Miroslav , Cankovic, Milenko , Dabovic, Dragana , Zivanovic, Zeljko , Stanetic, Bojan , Iveljic, Ivana , Nikolic, Dusan , Aleksandric, Srdjan , Beleslin, Branko Dusan

  • April 24, 2026

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