Relationship between endometrial VFI values detected by three-dimensional power Doppler ultrasound and pregnancy outcomes in FET patients and prediction of the optimal VFI range—a retrospective cohort study - Summary - MDSpire

Relationship between endometrial VFI values detected by three-dimensional power Doppler ultrasound and pregnancy outcomes in FET patients and prediction of the optimal VFI range—a retrospective cohort study

  • By

  • Run Zhao

  • Linlin Che

  • Xiaofang Li

  • Qianyan Song

  • Lihong Zhou

  • Siyu Long

  • Yu Zhang

  • June 5, 2026

  • 0 min

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Objective:

To explore the relationship between three-dimensional energy Doppler ultrasound-detected VFI and pregnancy outcomes in FET patients and to determine the appropriate range of endometrial VFI.

Key Findings:
  • Abortion rates in Group 3 and Group 4 were significantly lower than in Group 1 (p < 0.05).
  • Adjusted odds ratios for abortion risk were 0.210 for Group 3 and 0.227 for Group 4 compared to Group 1 (p < 0.05).
  • A significant linear negative correlation was found between endometrial VFI and abortion rate, with a threshold of 0.1698045.
Interpretation:

Endometrial VFI values measured by 3D energy Doppler ultrasound can predict miscarriage risk in FET patients, with values above 0.17 indicating better pregnancy prognosis.

Limitations:
  • Retrospective design may introduce selection bias.
  • Study limited to a single center, which may affect generalizability.
Conclusion:

Endometrial VFI values can serve as a predictive indicator for miscarriage risk in FET patients, with a VFI threshold of > 0.17 being significant for clinical evaluation.

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