The effect of preoperative stellate ganglion block on postoperative delirium in elderly patients undergoing gastrointestinal oncologic surgery: protocol for a randomized, double-blind, sham-controlled trial - Summary - MDSpire

The effect of preoperative stellate ganglion block on postoperative delirium in elderly patients undergoing gastrointestinal oncologic surgery: protocol for a randomized, double-blind, sham-controlled trial

  • By

  • Rongrong Song

  • Yuqin Huang

  • Jie Liu

  • Xingyu Wang

  • Yuqian Liu

  • Fanli Wang

  • Fang Wu

  • XiaXia Li

  • Yang Liu

  • Lu Cao

  • Yan Liu

  • Guojieying Wang

  • Minghong Gui

  • Yingbin Wang

  • Xiangfei Huang

  • June 16, 2026

  • 0 min

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Objective:

To compare the effect of preoperative ultrasound-guided stellate ganglion block (SGB) versus sham block on the 3-day cumulative incidence of postoperative delirium (POD) in elderly patients undergoing gastrointestinal cancer surgery.

Approach:
    Key Findings:
    • POD occurs in 35%~48% of elderly patients undergoing gastrointestinal surgery and is linked to poor outcomes.
    • Current pharmacological prevention strategies for POD are limited, necessitating novel interventions.
    • SGB may reduce postoperative pain and inflammatory markers, but direct evidence for preventing POD in humans is lacking.
    Interpretation:

    Remove this section.

    Limitations:
    • The assumed effect size of SGB may be optimistic.
    • No participants have been enrolled or randomized as of the manuscript submission.
    Conclusion:

    Remove this section.

    Sources:

Original Source(s)

The effect of preoperative stellate ganglion block on postoperative delirium in elderly patients undergoing gastrointestinal oncologic surgery: protocol for a randomized, double-blind, sham-controlled trial

  • by Rongrong Song, Yuqin Huang, Jie Liu, Xingyu Wang, Yuqian Liu, Fanli Wang, Fang Wu, XiaXia Li, Yang Liu, Lu Cao, Yan Liu, Guojieying Wang, Minghong Gui, Yingbin Wang, Xiangfei Huang

  • June 16, 2026

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