Acute acalculous cholecystitis in children due to EBV and cytomegalovirus infection: a rare case report and review of the literature - Summary - MDSpire

Acute acalculous cholecystitis in children due to EBV and cytomegalovirus infection: a rare case report and review of the literature

  • By

  • Wenling Ding

  • Renchang Liu

  • June 22, 2026

  • 0 min

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Objective:

To report a case of acute acalculous cholecystitis (AAC) in a child associated with Epstein-Barr virus (EBV) and cytomegalovirus (CMV) coinfection during infectious mononucleosis.

Approach:
    Key Findings:
    • The patient had EBV and CMV coinfection, leading to AAC during infectious mononucleosis.
    • Clinical presentation included fever, abdominal pain, lymphadenopathy, and elevated liver enzymes.
    • Conservative management was effective, avoiding unnecessary surgical intervention.
    Interpretation:

    Limitations:
    • The rarity of AAC in children may limit generalizability of findings.
    • Further studies are needed to understand the mechanisms of EBV and CMV coinfection in AAC.
    Conclusion:

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