Impact of Sleeve Gastrectomy on Skeletal Health: An Overlooked Concern - Summary - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Effects of Sleeve Gastrectomy on Bone Health: A Neglected Issue

  • By

  • Peter R Ebeling

  • January 20, 2025

Share

Objective:

To elucidate the skeletal effects of sleeve gastrectomy, particularly in relation to sex and menopausal status, and to explicitly compare them to those following Roux-en-Y gastric bypass (RYGB).

Key Findings:
  • Mean weight loss after 12 months was 28.8%.
  • Fractional calcium absorption decreased by 17.9% at 6 months.
  • Areal BMD decreased at femoral neck (−6.7%) and total hip (−8.0%), while spinal aBMD decreased minimally (−1.3%).
  • Tibial and radial microstructure worsened, with tibial estimated strength also decreasing.
  • Postmenopausal women exhibited greater declines in bone health variables compared to men, indicating a higher risk.
Interpretation:

Skeletal health should be a focus in patients undergoing sleeve gastrectomy, as significant bone loss occurs, particularly in postmenopausal women, which may increase fracture risk and necessitate clinical monitoring.

Limitations:
  • Small sample size of 54 participants.
  • Lack of long-term follow-up beyond 12 months, which may limit the generalizability of findings.
Conclusion:

Bone health in sleeve gastrectomy patients is critical and parallels some adverse effects seen after RYGB. Increased monitoring and potential pharmacotherapy may be necessary for at-risk groups, particularly postmenopausal women.

Original Source(s)

Impact of Sleeve Gastrectomy on Skeletal Health: An Overlooked Concern

  • by Peter R Ebeling

  • January 20, 2025

Related Content

Top 10 States With Rising Demand for Physicians

These 10 states report physician shortages, projected physician supply gaps, or physician-to-population ratios below national benchmarks.

Medical Oddities: Natural Doesn't Always Mean Safe

From the gym to the kitchen to romance, these studies challenge everyday assumptions.

Lower BMI, Lower Joint Replacement Risk?

Researchers urge caution in interpreting joint replacement predictors, noting that surgery reflects access and decision-making as well as disease biology.