To investigate associations between adverse events during surgery and oncological outcomes, including recurrence, prostate cancer-specific mortality, and all-cause mortality within 12 years.
Key Findings:
Adverse events during surgery were associated with higher recurrence rates, indicating a potential area for intervention.
RALP showed lower prostate cancer-specific mortality compared to ORP after 12 years, suggesting a long-term benefit of the robotic approach.
Known risk factors for recurrence included higher age, tumor grade, advanced tumor stage, and positive surgical margins, which should be considered in preoperative assessments.
Interpretation:
Difficulties encountered during surgery may impact the radicality of the procedure and the immunological response to cancer cells, potentially influencing recurrence and mortality outcomes.
Limitations:
The non-randomized design may introduce bias, limiting the generalizability of the findings.
Adverse events were not systematically documented in all studies, which could affect the comprehensiveness of the data.
Conclusion:
Adverse events during radical prostatectomy are linked to worse oncological outcomes, emphasizing the need for meticulous surgical technique to minimize complications.
