Perceived stress and mental health in perimenopausal women: a serial mediation study of psychological distress and social support - Summary - MDSpire

Perceived stress and mental health in perimenopausal women: a serial mediation study of psychological distress and social support

  • By

  • Tingting Ruan

  • Ying Yuan

  • Yiwei Li

  • Lijia Hou

  • Xuyan Liu

  • Shuling Ye

  • Jing Lu

  • Xue Tang

  • Yang Liu

  • May 20, 2026

  • 0 min

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Objective:

To examine how social support mediates the relationship between perceived stress and psychological symptom severity in perimenopausal women.

Key Findings:
  • Perceived stress is positively correlated with psychological distress and symptom severity.
  • Perceived social support is negatively correlated with perceived stress, psychological distress, and symptom severity.
  • Perceived stress significantly increases psychological symptom severity scores after adjusting for confounding variables.
  • Psychological distress and perceived social support independently mediate the relationship between perceived stress and symptom severity.
Interpretation:

Stress directly increases psychological symptom severity in perimenopausal women, with psychological distress and social support acting as mediators.

Limitations:
  • Cross-sectional design limits causal inferences.
  • Sample limited to Chinese women, affecting generalizability.
Conclusion:

Addressing psychological distress and enhancing social support are essential for improving mental health in perimenopausal women.

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