Perceived stress and mental health in perimenopausal women: a serial mediation study of psychological distress and social support
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By
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Tingting Ruan
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Ying Yuan
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Yiwei Li
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Lijia Hou
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Xuyan Liu
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Shuling Ye
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Jing Lu
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Xue Tang
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Yang Liu
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May 20, 2026
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Objective:
To examine how social support mediates the relationship between perceived stress and psychological symptom severity in perimenopausal women.
Key Findings:
- Perceived stress is positively correlated with psychological distress and symptom severity.
- Perceived social support is negatively correlated with perceived stress, psychological distress, and symptom severity.
- Perceived stress significantly increases psychological symptom severity scores after adjusting for confounding variables.
- Psychological distress and perceived social support independently mediate the relationship between perceived stress and symptom severity.
Interpretation:
Stress directly increases psychological symptom severity in perimenopausal women, with psychological distress and social support acting as mediators.
Limitations:
- Cross-sectional design limits causal inferences.
- Sample limited to Chinese women, affecting generalizability.
Conclusion:
Addressing psychological distress and enhancing social support are essential for improving mental health in perimenopausal women.