Risk factors for inferior right hepatic vein occlusion following right lobe living donor liver transplantation: a single-center experience with 240 cases - Summary - MDSpire

Risk factors for inferior right hepatic vein occlusion following right lobe living donor liver transplantation: a single-center experience with 240 cases

  • By

  • Adil Başkıran

  • Metin Kement

  • Deniz Yavuz Başkıran

  • Emrah Ülker

  • İpek Balıkçı Çiçek

  • Cemalettin Koç

  • Sertac Usta

  • Sezai Yılmaz

  • June 30, 2026

  • 0 min

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Objective:

To analyze early and long-term outcomes of inferior right hepatic vein (IRHV) reconstruction in right lobe living donor liver transplantation (RL-LDLT) and identify associated risk factors.

Approach:
  • Study Design: Retrospective cohort study of RL-LDLT recipients who underwent IRHV reconstruction from January 2021 to December 2023.
  • Patient Selection: Included patients who underwent IRHV reconstruction; excluded those with incomplete data, perioperative mortality, or anatomical variations preventing reconstruction.
  • Data Collection: Data collected from electronic medical records, surgical reports, and imaging studies, categorized into preoperative, intraoperative, and postoperative variables.
  • Surgical Techniques: Reconstruction classified as direct anastomosis, simple venoplasty, or complex venoplasty based on the surgical approach.
  • Postoperative Evaluation: IRHV patency assessed via multidetector computed tomography (MDCT) within the first 30 days and during long-term follow-ups.
  • Statistical Analysis: Used IBM SPSS Statistics for analysis, including ROC curve analysis and logistic regression to identify predictors of IRHV occlusion.
Key Findings:
  • The study included 240 RL-LDLT cases with different IRHV reconstruction techniques.
  • IRHV occlusion was linked to specific preoperative anatomical and clinical factors.
  • The optimal IRHV diameter threshold for occlusion risk was identified through ROC curve analysis.
Interpretation:

Identifying high-risk patients based on anatomical and clinical factors can facilitate personalized surgical planning to improve transplant outcomes.

Limitations:
  • The retrospective design may introduce selection bias.
  • Findings from a single-center study may not be generalizable.
Conclusion:

The study provides insights into risk factors for IRHV occlusion.

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